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3htz

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[[Image:3htz.png|left|200px]]
 
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{{STRUCTURE_3htz| PDB=3htz | SCENE= }}
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==Crystal Structure of the catalytic fragment of alanyl-tRNA synthetase in complex with L-serine: Re-refined==
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<StructureSection load='3htz' size='340' side='right'caption='[[3htz]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===Crystal Structure of the catalytic fragment of alanyl-tRNA synthetase in complex with L-serine: Re-refined===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3htz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HTZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HTZ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3htz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3htz OCA], [https://pdbe.org/3htz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3htz RCSB], [https://www.ebi.ac.uk/pdbsum/3htz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3htz ProSAT]</span></td></tr>
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[[3htz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HTZ OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SYA_AQUAE SYA_AQUAE] Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity).[HAMAP-Rule:MF_00036]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ht/3htz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3htz ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
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[[Category: Alanine--tRNA ligase]]
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__TOC__
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</StructureSection>
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
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[[Category: Guo, M.]]
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[[Category: Large Structures]]
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[[Category: Schimmel, P.]]
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[[Category: Guo M]]
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[[Category: Swairjo, M A.]]
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[[Category: Schimmel P]]
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[[Category: Adenosine triphosphate]]
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[[Category: Swairjo MA]]
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[[Category: Alanine-trna ligase]]
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[[Category: Aminoacyl-trna synthetase]]
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[[Category: Atp-binding]]
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[[Category: Binding site]]
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[[Category: Genetic code]]
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[[Category: Ligase]]
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[[Category: Nucleotide-binding]]
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[[Category: Protein biosynthesis]]
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[[Category: Protein conformation]]
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Current revision

Crystal Structure of the catalytic fragment of alanyl-tRNA synthetase in complex with L-serine: Re-refined

PDB ID 3htz

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