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1dlk

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[[Image:1dlk.png|left|200px]]
 
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{{STRUCTURE_1dlk| PDB=1dlk | SCENE= }}
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==CRYSTAL STRUCTURE ANALYSIS OF DELTA-CHYMOTRYPSIN BOUND TO A PEPTIDYL CHLOROMETHYL KETONE INHIBITOR==
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<StructureSection load='1dlk' size='340' side='right'caption='[[1dlk]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
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===CRYSTAL STRUCTURE ANALYSIS OF DELTA-CHYMOTRYPSIN BOUND TO A PEPTIDYL CHLOROMETHYL KETONE INHIBITOR===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1dlk]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DLK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DLK FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10713514}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.14&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0QE:CHLOROMETHANE'>0QE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HPH:(2S)-2-AMINO-3-PHENYLPROPANE-1,1-DIOL'>HPH</scene>, <scene name='pdbligand=PHQ:BENZYL+CHLOROCARBONATE'>PHQ</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dlk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dlk OCA], [https://pdbe.org/1dlk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dlk RCSB], [https://www.ebi.ac.uk/pdbsum/1dlk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dlk ProSAT]</span></td></tr>
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[[1dlk]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DLK OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CTRA_BOVIN CTRA_BOVIN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dl/1dlk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dlk ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Chymotrypsin|Chymotrypsin]]
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*[[Thrombin 3D Structures|Thrombin 3D Structures]]
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*[[Thrombin|Thrombin]]
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__TOC__
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:010713514</ref><references group="xtra"/>
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Chymotrypsin]]
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[[Category: Large Structures]]
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[[Category: Birrane, G.]]
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[[Category: Birrane G]]
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[[Category: Connell, T O.]]
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[[Category: Mac Sweeney A]]
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[[Category: Malthouse, J P.G.]]
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[[Category: Malthouse JPG]]
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[[Category: Sweeney, A Mac.]]
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[[Category: O'Connell T]]
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[[Category: Walsh, M A.]]
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[[Category: Walsh MA]]
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[[Category: Chloromethyl ketone]]
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[[Category: Delta-chymotrypsin]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Peptidic inhibior]]
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Current revision

CRYSTAL STRUCTURE ANALYSIS OF DELTA-CHYMOTRYPSIN BOUND TO A PEPTIDYL CHLOROMETHYL KETONE INHIBITOR

PDB ID 1dlk

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