1sqe
From Proteopedia
(Difference between revisions)
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:1sqe.png|left|200px]] | ||
| - | + | ==1.5A Crystal Structure Of the protein PG130 from Staphylococcus aureus, Structural genomics== | |
| - | + | <StructureSection load='1sqe' size='340' side='right'caption='[[1sqe]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1sqe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SQE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sqe OCA], [https://pdbe.org/1sqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sqe RCSB], [https://www.ebi.ac.uk/pdbsum/1sqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sqe ProSAT], [https://www.topsan.org/Proteins/MCSG/1sqe TOPSAN]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1sqe]] is a 2 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/HDOX2_STAAM HDOX2_STAAM] Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.[HAMAP-Rule:MF_01272] | |
| - | == | + | == Evolutionary Conservation == |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | + | Check<jmol> | |
| - | == | + | <jmolCheckbox> |
| - | < | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sq/1sqe_consurf.spt"</scriptWhenChecked> |
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sqe ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Staphylococcus aureus]] | [[Category: Staphylococcus aureus]] | ||
| - | [[Category: Joachimiak | + | [[Category: Joachimiak A]] |
| - | [[Category: Joachimiak | + | [[Category: Joachimiak G]] |
| - | + | [[Category: Schneewind O]] | |
| - | [[Category: Schneewind | + | [[Category: Wu R]] |
| - | [[Category: Wu | + | [[Category: Zhang R]] |
| - | [[Category: Zhang | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
1.5A Crystal Structure Of the protein PG130 from Staphylococcus aureus, Structural genomics
| |||||||||||
