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1pyt

From Proteopedia

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[[Image:1pyt.png|left|200px]]
 
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{{STRUCTURE_1pyt| PDB=1pyt | SCENE= }}
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==TERNARY COMPLEX OF PROCARBOXYPEPTIDASE A, PROPROTEINASE E, AND CHYMOTRYPSINOGEN C==
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<StructureSection load='1pyt' size='340' side='right'caption='[[1pyt]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
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===TERNARY COMPLEX OF PROCARBOXYPEPTIDASE A, PROPROTEINASE E, AND CHYMOTRYPSINOGEN C===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1pyt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PYT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PYT FirstGlance]. <br>
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{{ABSTRACT_PUBMED_7556081}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pyt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pyt OCA], [https://pdbe.org/1pyt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pyt RCSB], [https://www.ebi.ac.uk/pdbsum/1pyt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pyt ProSAT]</span></td></tr>
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[[1pyt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PYT OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CBPA1_BOVIN CBPA1_BOVIN] Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/py/1pyt_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pyt ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Carboxypeptidase|Carboxypeptidase]]
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*[[Carboxypeptidase 3D structures|Carboxypeptidase 3D structures]]
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*[[Chymotrypsin 3D structures|Chymotrypsin 3D structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:007556081</ref><ref group="xtra">PMID:009223647</ref><ref group="xtra">PMID:018059268</ref><references group="xtra"/>
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</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Carboxypeptidase A]]
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[[Category: Large Structures]]
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[[Category: Aviles, F X.]]
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[[Category: Aviles FX]]
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[[Category: Bode, W.]]
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[[Category: Bode W]]
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[[Category: Gomez, M.]]
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[[Category: Gomez M]]
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[[Category: Gomis-Ruth, F X.]]
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[[Category: Gomis-Ruth FX]]
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[[Category: Huber, R.]]
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[[Category: Huber R]]
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[[Category: C-terminal peptidase]]
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[[Category: Serine proteinase]]
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Current revision

TERNARY COMPLEX OF PROCARBOXYPEPTIDASE A, PROPROTEINASE E, AND CHYMOTRYPSINOGEN C

PDB ID 1pyt

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