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1nx0

From Proteopedia

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[[Image:1nx0.png|left|200px]]
 
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{{STRUCTURE_1nx0| PDB=1nx0 | SCENE= }}
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==Structure of Calpain Domain 6 in Complex with Calpastatin DIC==
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<StructureSection load='1nx0' size='340' side='right'caption='[[1nx0]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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===Structure of Calpain Domain 6 in Complex with Calpastatin DIC===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1nx0]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NX0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NX0 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12684003}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nx0 OCA], [https://pdbe.org/1nx0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nx0 RCSB], [https://www.ebi.ac.uk/pdbsum/1nx0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nx0 ProSAT]</span></td></tr>
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[[1nx0]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NX0 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CPNS1_PIG CPNS1_PIG] Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nx/1nx0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nx0 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Calpain|Calpain]]
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*[[Calpain 3D structures|Calpain 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:012684003</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Chattopadhyay, D.]]
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[[Category: Chattopadhyay D]]
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[[Category: Deivanayagam, C C.S.]]
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[[Category: Deivanayagam CCS]]
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[[Category: Lin, G D.]]
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[[Category: Lin G-D]]
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[[Category: Maki, M.]]
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[[Category: Maki M]]
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[[Category: Moore, D.]]
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[[Category: Moore D]]
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[[Category: Narayana, S V.L.]]
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[[Category: Narayana SVL]]
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[[Category: Todd, B.]]
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[[Category: Todd B]]
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[[Category: Wang, K K.W.]]
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[[Category: Wang KKW]]
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[[Category: Calcium binding]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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Current revision

Structure of Calpain Domain 6 in Complex with Calpastatin DIC

PDB ID 1nx0

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