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1lp4

From Proteopedia

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[[Image:1lp4.png|left|200px]]
 
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{{STRUCTURE_1lp4| PDB=1lp4 | SCENE= }}
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==Crystal structure of a binary complex of the catalytic subunit of protein kinase CK2 with Mg-AMPPNP==
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<StructureSection load='1lp4' size='340' side='right'caption='[[1lp4]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
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===Crystal structure of a binary complex of the catalytic subunit of protein kinase CK2 with Mg-AMPPNP===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1lp4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LP4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LP4 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15740749}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lp4 OCA], [https://pdbe.org/1lp4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lp4 RCSB], [https://www.ebi.ac.uk/pdbsum/1lp4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lp4 ProSAT]</span></td></tr>
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[[1lp4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LP4 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CSK2A_MAIZE CSK2A_MAIZE] Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lp/1lp4_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lp4 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Casein kinase|Casein kinase]]
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*[[Casein kinase 3D structures|Casein kinase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:015740749</ref><ref group="xtra">PMID:009564028</ref><ref group="xtra">PMID:009761839</ref><ref group="xtra">PMID:010581548</ref><ref group="xtra">PMID:011574463</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Zea mays]]
[[Category: Zea mays]]
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[[Category: Guerra, B.]]
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[[Category: Guerra B]]
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[[Category: Issinger, O G.]]
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[[Category: Issinger O-G]]
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[[Category: Niefind, K.]]
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[[Category: Niefind K]]
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[[Category: Puetter, M.]]
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[[Category: Puetter M]]
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[[Category: Schomburg, D.]]
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[[Category: Schomburg D]]
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[[Category: Casein kinase 2]]
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[[Category: Ck2]]
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[[Category: Dual-cosubstrate specificity]]
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[[Category: Protein kinase]]
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[[Category: Transferase]]
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Current revision

Crystal structure of a binary complex of the catalytic subunit of protein kinase CK2 with Mg-AMPPNP

PDB ID 1lp4

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