2r5j
From Proteopedia
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| - | [[Image:2r5j.png|left|200px]] | ||
| - | + | ==Pentamer Structure of Major Capsid protein L1 of Human Papilloma Virus Type 35== | |
| - | + | <StructureSection load='2r5j' size='340' side='right'caption='[[2r5j]], [[Resolution|resolution]] 3.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2r5j]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_papillomavirus_35 Human papillomavirus 35]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R5J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R5J FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r5j OCA], [https://pdbe.org/2r5j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r5j RCSB], [https://www.ebi.ac.uk/pdbsum/2r5j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r5j ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[2r5j]] is a 15 chain structure with sequence from [ | + | == Function == |
| + | [https://www.uniprot.org/uniprot/VL1_HPV35 VL1_HPV35] Forms an icosahedral capsid with a T=7 symmetry and about 55 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. The capsid encapsulates the genomic DNA, but does not bind DNA. Essential for the initial attachment to the host cell (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r5/2r5j_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r5j ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Virus coat | + | *[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Human papillomavirus 35]] | |
| - | [[Category: Human papillomavirus | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Bishop B]] |
| - | [[Category: | + | [[Category: Chen XS]] |
| - | [[Category: | + | [[Category: Dasgupta J]] |
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Current revision
Pentamer Structure of Major Capsid protein L1 of Human Papilloma Virus Type 35
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