3s14

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[[Image:3s14.png|left|200px]]
 
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{{STRUCTURE_3s14| PDB=3s14 | SCENE= }}
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==RNA Polymerase II Initiation Complex with a 6-nt RNA==
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<StructureSection load='3s14' size='340' side='right'caption='[[3s14]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
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===RNA Polymerase II Initiation Complex with a 6-nt RNA===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3s14]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S14 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S14 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21798951}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s14 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s14 OCA], [https://pdbe.org/3s14 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s14 RCSB], [https://www.ebi.ac.uk/pdbsum/3s14 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s14 ProSAT]</span></td></tr>
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[[3s14]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S14 OCA].
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</table>
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== Function ==
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==See Also==
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[https://www.uniprot.org/uniprot/RPB3_YEAST RPB3_YEAST] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft. Seems to be involved in transcription termination.
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*[[RNA polymerase|RNA polymerase]]
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__TOC__
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</StructureSection>
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==Reference==
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[[Category: Large Structures]]
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<ref group="xtra">PMID:021798951</ref><references group="xtra"/>
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: DNA-directed RNA polymerase]]
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[[Category: Bushnell DA]]
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[[Category: Saccharomyces cerevisiae s288c]]
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[[Category: Huang X]]
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[[Category: Bushnell, D A.]]
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[[Category: Kornberg RD]]
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[[Category: Huang, X.]]
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[[Category: Liu X]]
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[[Category: Kornberg, R D.]]
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[[Category: Silva DA]]
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[[Category: Liu, X.]]
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[[Category: Silva, D A.]]
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[[Category: Initiation complex]]
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[[Category: Rna polymerase ii]]
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[[Category: Transcription-rna-dna complex]]
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Current revision

RNA Polymerase II Initiation Complex with a 6-nt RNA

PDB ID 3s14

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OCA

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