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1jje

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[[Image:1jje.png|left|200px]]
 
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{{STRUCTURE_1jje| PDB=1jje | SCENE= }}
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==IMP-1 METALLO BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH A BIARYL SUCCINIC ACID INHIBITOR (11)==
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<StructureSection load='1jje' size='340' side='right'caption='[[1jje]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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===IMP-1 METALLO BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH A BIARYL SUCCINIC ACID INHIBITOR (11)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1jje]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JJE FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11390410}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BYS:2-BENZO[1,3]DIOXOL-5-YLMETHYL-3-BENZYL-SUCCINIC+ACID'>BYS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jje OCA], [https://pdbe.org/1jje PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jje RCSB], [https://www.ebi.ac.uk/pdbsum/1jje PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jje ProSAT]</span></td></tr>
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[[1jje]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJE OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q79MP6_PSEAI Q79MP6_PSEAI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jj/1jje_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jje ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Beta-lactamase|Beta-lactamase]]
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:011390410</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Beta-lactamase]]
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[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Fitzgerald, P M.D.]]
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[[Category: Fitzgerald PMD]]
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[[Category: Sharma, N.]]
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[[Category: Sharma N]]
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[[Category: Hydrolase]]
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[[Category: Imp-1 metallo-beta-lactamase]]
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[[Category: Metallo-beta-lactamase inhibitor]]
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[[Category: Succinic acid inhibitor]]
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Current revision

IMP-1 METALLO BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH A BIARYL SUCCINIC ACID INHIBITOR (11)

PDB ID 1jje

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