This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2dn8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (18:44, 29 May 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2dn8.png|left|200px]]
 
-
{{STRUCTURE_2dn8| PDB=2dn8 | SCENE= }}
+
==Solution Structure of RSGI RUH-053, an Apo-Biotin Carboxy Carrier Protein from Human Transcarboxylase==
-
 
+
<StructureSection load='2dn8' size='340' side='right'caption='[[2dn8]]' scene=''>
-
===Solution Structure of RSGI RUH-053, an Apo-Biotin Carboxy Carrier Protein from Human Transcarboxylase===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2dn8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DN8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DN8 FirstGlance]. <br>
-
 
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dn8 OCA], [https://pdbe.org/2dn8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dn8 RCSB], [https://www.ebi.ac.uk/pdbsum/2dn8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dn8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dn8 TOPSAN]</span></td></tr>
-
[[2dn8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DN8 OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ACACB_HUMAN ACACB_HUMAN] ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dn/2dn8_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dn8 ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Acetyl-CoA carboxylase|Acetyl-CoA carboxylase]]
+
*[[Acetyl-CoA carboxylase 3D structures|Acetyl-CoA carboxylase 3D structures]]
-
[[Category: Acetyl-CoA carboxylase]]
+
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Hayashi, F.]]
+
[[Category: Large Structures]]
-
[[Category: Hirota, H.]]
+
[[Category: Hayashi F]]
-
[[Category: Momen, A Z.M Ruhul.]]
+
[[Category: Hirota H]]
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
[[Category: Ruhul Momen AZM]]
-
[[Category: Yokoyama, S.]]
+
[[Category: Yokoyama S]]
-
[[Category: Acetyl coa carboxylase]]
+
-
[[Category: Biotin required enzyme]]
+
-
[[Category: Ligase]]
+
-
[[Category: National project on protein structural and functional analyse]]
+
-
[[Category: Nppsfa]]
+
-
[[Category: Riken structural genomics/proteomics initiative]]
+
-
[[Category: Rsgi]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Transcarboxylase]]
+

Current revision

Solution Structure of RSGI RUH-053, an Apo-Biotin Carboxy Carrier Protein from Human Transcarboxylase

PDB ID 2dn8

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools