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1fsk

From Proteopedia

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[[Image:1fsk.png|left|200px]]
 
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{{STRUCTURE_1fsk| PDB=1fsk | SCENE= }}
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==COMPLEX FORMATION BETWEEN A FAB FRAGMENT OF A MONOCLONAL IGG ANTIBODY AND THE MAJOR ALLERGEN FROM BIRCH POLLEN BET V 1==
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<StructureSection load='1fsk' size='340' side='right'caption='[[1fsk]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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===COMPLEX FORMATION BETWEEN A FAB FRAGMENT OF A MONOCLONAL IGG ANTIBODY AND THE MAJOR ALLERGEN FROM BIRCH POLLEN BET V 1===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1fsk]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Betula_pendula Betula pendula] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FSK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FSK FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10861069}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fsk OCA], [https://pdbe.org/1fsk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fsk RCSB], [https://www.ebi.ac.uk/pdbsum/1fsk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fsk ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1fsk]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Betula_pendula Betula pendula] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FSK OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/BEV1A_BETPN BEV1A_BETPN] May be a general steroid carrier protein (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fs/1fsk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fsk ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Monoclonal Antibody|Monoclonal Antibody]]
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
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==Reference==
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*[[3D structures of non-human antibody|3D structures of non-human antibody]]
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<ref group="xtra">PMID:010861069</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Betula pendula]]
[[Category: Betula pendula]]
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Gajhede, M.]]
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[[Category: Gajhede M]]
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[[Category: Henriksen, A.]]
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[[Category: Henriksen A]]
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[[Category: Ipsen, H.]]
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[[Category: Ipsen H]]
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[[Category: Larsen, J.]]
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[[Category: Larsen J]]
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[[Category: Mirza, O.]]
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[[Category: Mirza O]]
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[[Category: Spangfort, M.]]
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[[Category: Spangfort M]]
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[[Category: Wissenbach, M.]]
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[[Category: Wissenbach M]]
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[[Category: Antibody allergen complex]]
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[[Category: Bet v 1]]
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[[Category: Bv16 fab fragment]]
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[[Category: Immune system]]
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Current revision

COMPLEX FORMATION BETWEEN A FAB FRAGMENT OF A MONOCLONAL IGG ANTIBODY AND THE MAJOR ALLERGEN FROM BIRCH POLLEN BET V 1

PDB ID 1fsk

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