This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3ero

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:32, 6 September 2023) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3ero.png|left|200px]]
 
-
{{STRUCTURE_3ero| PDB=3ero | SCENE= }}
+
==Crystal structure of Staphylococcal nuclease variant Delta+PHS I72E at cryogenic temperature==
-
 
+
<StructureSection load='3ero' size='340' side='right'caption='[[3ero]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
-
===Crystal structure of Staphylococcal nuclease variant Delta+PHS I72E at cryogenic temperature===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[3ero]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ERO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ERO FirstGlance]. <br>
-
 
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
-
==About this Structure==
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr>
-
[[3ero]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ERO OCA].
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ero FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ero OCA], [https://pdbe.org/3ero PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ero RCSB], [https://www.ebi.ac.uk/pdbsum/3ero PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ero ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/er/3ero_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ero ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Staphylococcal nuclease|Staphylococcal nuclease]]
+
*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
-
[[Category: Micrococcal nuclease]]
+
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
-
[[Category: Garcia-Moreno, E B.]]
+
[[Category: Garcia-Moreno EB]]
-
[[Category: Robinson, A C.]]
+
[[Category: Robinson AC]]
-
[[Category: Schlessman, J L.]]
+
[[Category: Schlessman JL]]
-
[[Category: Endonuclease]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Hyperstable variant]]
+
-
[[Category: Membrane]]
+
-
[[Category: Metal-binding]]
+
-
[[Category: Nuclease]]
+
-
[[Category: Pdtp]]
+
-
[[Category: Secreted]]
+
-
[[Category: Staphylococcal nuclease]]
+
-
[[Category: Zymogen]]
+

Current revision

Crystal structure of Staphylococcal nuclease variant Delta+PHS I72E at cryogenic temperature

PDB ID 3ero

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools