3rbl

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[[Image:3rbl.png|left|200px]]
 
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{{STRUCTURE_3rbl| PDB=3rbl | SCENE= }}
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==Crystal structure of Human aromatic L-amino acid decarboxylase (AADC) in the apo form==
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<StructureSection load='3rbl' size='340' side='right'caption='[[3rbl]], [[Resolution|resolution]] 3.24&Aring;' scene=''>
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===Crystal structure of Human aromatic L-amino acid decarboxylase (AADC) in the apo form===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3rbl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RBL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RBL FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22143761}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.24&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rbl OCA], [https://pdbe.org/3rbl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rbl RCSB], [https://www.ebi.ac.uk/pdbsum/3rbl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rbl ProSAT]</span></td></tr>
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[[3rbl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RBL OCA].
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/DDC_HUMAN DDC_HUMAN] Aromatic L-amino acid decarboxylase deficiency. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/DDC_HUMAN DDC_HUMAN] Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
==See Also==
==See Also==
*[[DOPA decarboxylase|DOPA decarboxylase]]
*[[DOPA decarboxylase|DOPA decarboxylase]]
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*[[User:Brian Hernandez/DOPA Decarboxylase|User:Brian Hernandez/DOPA Decarboxylase]]
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__TOC__
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:022143761</ref><references group="xtra"/>
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[[Category: Aromatic-L-amino-acid decarboxylase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Cellini, B.]]
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[[Category: Large Structures]]
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[[Category: Cutruzzola, F.]]
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[[Category: Borri Voltattorni C]]
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[[Category: Gianni, S.]]
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[[Category: Cellini B]]
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[[Category: Giardina, G.]]
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[[Category: Cutruzzola F]]
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[[Category: Montioli, R.]]
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[[Category: Gianni S]]
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[[Category: Paiardini, A.]]
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[[Category: Giardina G]]
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[[Category: Voltattorni, C Borri.]]
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[[Category: Montioli R]]
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[[Category: Aadc deficiency]]
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[[Category: Paiardini A]]
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[[Category: Apo enzyme]]
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[[Category: Apo form]]
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[[Category: Conformational change]]
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[[Category: Ddc]]
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[[Category: Decarboxylase]]
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[[Category: Exposed]]
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[[Category: L-dopa]]
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[[Category: Lyase]]
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[[Category: Open conformation]]
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[[Category: Open dimer]]
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[[Category: Parkinson]]
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[[Category: Plp]]
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Current revision

Crystal structure of Human aromatic L-amino acid decarboxylase (AADC) in the apo form

PDB ID 3rbl

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