2nzl

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:27, 30 August 2023) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2nzl.png|left|200px]]
 
-
{{STRUCTURE_2nzl| PDB=2nzl | SCENE= }}
+
==Crystal structure of human hydroxyacid oxidase 1==
-
 
+
<StructureSection load='2nzl' size='340' side='right'caption='[[2nzl]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
-
===Crystal structure of human hydroxyacid oxidase 1===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2nzl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NZL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NZL FirstGlance]. <br>
-
 
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
-
==About this Structure==
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GLV:GLYOXYLIC+ACID'>GLV</scene></td></tr>
-
[[2nzl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NZL OCA].
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nzl OCA], [https://pdbe.org/2nzl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nzl RCSB], [https://www.ebi.ac.uk/pdbsum/2nzl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nzl ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/HAOX1_HUMAN HAOX1_HUMAN] Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nz/2nzl_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2nzl ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Glycolate oxidase|Glycolate oxidase]]
+
*[[Glycolate oxidase 3D structures|Glycolate oxidase 3D structures]]
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Large Structures]]
-
[[Category: Berridge, G.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Debreczeni, J E.]]
+
[[Category: Berridge G]]
-
[[Category: Delft, F Von.]]
+
[[Category: Debreczeni JE]]
-
[[Category: Edwards, A.]]
+
[[Category: Edwards A]]
-
[[Category: Gileadi, O.]]
+
[[Category: Gileadi O]]
-
[[Category: Kavanagh, K.]]
+
[[Category: Kavanagh K]]
-
[[Category: Niesen, F.]]
+
[[Category: Niesen F]]
-
[[Category: Oppermann, U.]]
+
[[Category: Oppermann U]]
-
[[Category: Papagrigoriou, E.]]
+
[[Category: Papagrigoriou E]]
-
[[Category: Pilka, E.]]
+
[[Category: Pilka E]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Sundstrom M]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Turnbull A]]
-
[[Category: Turnbull, A.]]
+
[[Category: Ugochukwu E]]
-
[[Category: Ugochukwu, E.]]
+
[[Category: Weigelt J]]
-
[[Category: Weigelt, J.]]
+
[[Category: Von Delft F]]
-
[[Category: Glycolate oxidase]]
+
-
[[Category: Gox]]
+
-
[[Category: Gox1]]
+
-
[[Category: Haox1]]
+
-
[[Category: Hydroxyacid oxidase 1]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Sgc]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Structural genomics consortium]]
+

Current revision

Crystal structure of human hydroxyacid oxidase 1

PDB ID 2nzl

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2nzl"
Personal tools