2d4a
From Proteopedia
(Difference between revisions)
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2d4a.png|left|200px]] | ||
| - | + | ==Structure of the malate dehydrogenase from Aeropyrum pernix== | |
| - | + | <StructureSection load='2d4a' size='340' side='right'caption='[[2d4a]], [[Resolution|resolution]] 2.87Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2d4a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D4A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D4A FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.87Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d4a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d4a OCA], [https://pdbe.org/2d4a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d4a RCSB], [https://www.ebi.ac.uk/pdbsum/2d4a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d4a ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[2d4a]] is a 4 chain structure with sequence from [ | + | == Function == |
| + | [https://www.uniprot.org/uniprot/MDH_AERPE MDH_AERPE] Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate. Can utilize both NAD and NADP. Has a preference for NADP.<ref>PMID:19555779</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d4/2d4a_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d4a ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | + | *[[Malate Dehydrogenase 3D structures|Malate Dehydrogenase 3D structures]] | |
| - | *[[Malate | + | == References == |
| - | + | <references/> | |
| - | == | + | __TOC__ |
| - | < | + | </StructureSection> |
[[Category: Aeropyrum pernix]] | [[Category: Aeropyrum pernix]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Kawakami | + | [[Category: Kawakami R]] |
| - | [[Category: Ohshima | + | [[Category: Ohshima T]] |
| - | [[Category: Sakuraba | + | [[Category: Sakuraba H]] |
| - | [[Category: Tsuge | + | [[Category: Tsuge H]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Structure of the malate dehydrogenase from Aeropyrum pernix
| |||||||||||
