3lz5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:47, 7 February 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3lz5.png|left|200px]]
 
-
{{STRUCTURE_3lz5| PDB=3lz5 | SCENE= }}
+
==Human aldose reductase mutant T113V complexed with IDD594==
-
 
+
<StructureSection load='3lz5' size='340' side='right'caption='[[3lz5]], [[Resolution|resolution]] 0.95&Aring;' scene=''>
-
===Human aldose reductase mutant T113V complexed with IDD594===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[3lz5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LZ5 FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_21185307}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.95&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=LDT:IDD594'>LDT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lz5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lz5 OCA], [https://pdbe.org/3lz5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lz5 RCSB], [https://www.ebi.ac.uk/pdbsum/3lz5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lz5 ProSAT]</span></td></tr>
-
[[3lz5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ5 OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
==See Also==
==See Also==
-
*[[Aldose Reductase|Aldose Reductase]]
+
*[[Aldose reductase 3D structures|Aldose reductase 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:021185307</ref><references group="xtra"/>
+
-
[[Category: Aldehyde reductase]]
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Heine, A.]]
+
[[Category: Large Structures]]
-
[[Category: Klebe, G.]]
+
[[Category: Heine A]]
-
[[Category: Koch, C.]]
+
[[Category: Klebe G]]
-
[[Category: Nadp]]
+
[[Category: Koch C]]
-
[[Category: Oxidoreductase]]
+
-
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
+
-
[[Category: Phosphoprotein]]
+
-
[[Category: T113v mutant]]
+
-
[[Category: Tim barrel]]
+

Current revision

Human aldose reductase mutant T113V complexed with IDD594

PDB ID 3lz5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools