1fnm

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[[Image:1fnm.png|left|200px]]
 
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{{STRUCTURE_1fnm| PDB=1fnm | SCENE= }}
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==STRUCTURE OF THERMUS THERMOPHILUS EF-G H573A==
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<StructureSection load='1fnm' size='340' side='right'caption='[[1fnm]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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===STRUCTURE OF THERMUS THERMOPHILUS EF-G H573A===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1fnm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FNM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FNM FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11054294}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fnm OCA], [https://pdbe.org/1fnm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fnm RCSB], [https://www.ebi.ac.uk/pdbsum/1fnm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fnm ProSAT]</span></td></tr>
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[[1fnm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FNM OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/EFG_THETH EFG_THETH] Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fn/1fnm_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fnm ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Elongation factor|Elongation factor]]
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*[[Elongation factor 3D structures|Elongation factor 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:011054294</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Gudkov, A T.]]
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[[Category: Gudkov AT]]
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[[Category: Hughes, D.]]
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[[Category: Hughes D]]
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[[Category: Kristensen, O.]]
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[[Category: Kristensen O]]
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[[Category: Laurberg, M.]]
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[[Category: Laurberg M]]
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[[Category: Liljas, A.]]
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[[Category: Liljas A]]
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[[Category: Martemyanov, K.]]
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[[Category: Martemyanov K]]
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[[Category: Nagaev, I.]]
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[[Category: Nagaev I]]
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[[Category: Bent conformation]]
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[[Category: Mutation his573ala]]
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[[Category: Translation]]
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[[Category: Visible domain iii]]
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Current revision

STRUCTURE OF THERMUS THERMOPHILUS EF-G H573A

PDB ID 1fnm

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