1fnm
From Proteopedia
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- | [[Image:1fnm.png|left|200px]] | ||
- | + | ==STRUCTURE OF THERMUS THERMOPHILUS EF-G H573A== | |
- | + | <StructureSection load='1fnm' size='340' side='right'caption='[[1fnm]], [[Resolution|resolution]] 2.80Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1fnm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FNM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FNM FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
- | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fnm OCA], [https://pdbe.org/1fnm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fnm RCSB], [https://www.ebi.ac.uk/pdbsum/1fnm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fnm ProSAT]</span></td></tr> |
- | [[1fnm]] is a 1 chain structure with sequence from [ | + | </table> |
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/EFG_THETH EFG_THETH] Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fn/1fnm_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fnm ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
- | *[[Elongation factor|Elongation factor]] | + | *[[Elongation factor 3D structures|Elongation factor 3D structures]] |
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | < | + | [[Category: Large Structures]] |
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
- | [[Category: Gudkov | + | [[Category: Gudkov AT]] |
- | [[Category: Hughes | + | [[Category: Hughes D]] |
- | [[Category: Kristensen | + | [[Category: Kristensen O]] |
- | [[Category: Laurberg | + | [[Category: Laurberg M]] |
- | [[Category: Liljas | + | [[Category: Liljas A]] |
- | [[Category: Martemyanov | + | [[Category: Martemyanov K]] |
- | [[Category: Nagaev | + | [[Category: Nagaev I]] |
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Current revision
STRUCTURE OF THERMUS THERMOPHILUS EF-G H573A
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