This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1p3q

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:52, 17 April 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1p3q.png|left|200px]]
 
-
{{STRUCTURE_1p3q| PDB=1p3q | SCENE= }}
+
==Mechanism of Ubiquitin Recognition by the CUE Domain of VPS9==
-
 
+
<StructureSection load='1p3q' size='340' side='right'caption='[[1p3q]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
-
===Mechanism of Ubiquitin Recognition by the CUE Domain of VPS9===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1p3q]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P3Q FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_12787502}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3q OCA], [https://pdbe.org/1p3q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p3q RCSB], [https://www.ebi.ac.uk/pdbsum/1p3q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p3q ProSAT]</span></td></tr>
-
[[1p3q]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3Q OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/VPS9_YEAST VPS9_YEAST] Required for vacuolar protein sorting; may be required for the consumption of transport vesicles containing vacuolar protein precursors. May bind a Rab GTPase such as VPS21.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p3/1p3q_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p3q ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Ubiquitin|Ubiquitin]]
+
*[[Vacuolar protein sorting-associated protein 3D structures|Vacuolar protein sorting-associated protein 3D structures]]
-
 
+
*[[3D structures of ubiquitin|3D structures of ubiquitin]]
-
==Reference==
+
__TOC__
-
<ref group="xtra">PMID:012787502</ref><references group="xtra"/>
+
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
 +
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
-
[[Category: Davies, B A.]]
+
[[Category: Davies BA]]
-
[[Category: Ghirlando, R.]]
+
[[Category: Ghirlando R]]
-
[[Category: Horazdovsky, B F.]]
+
[[Category: Horazdovsky BF]]
-
[[Category: Hurley, J H.]]
+
[[Category: Hurley JH]]
-
[[Category: Jones, E A.]]
+
[[Category: Jones EA]]
-
[[Category: Misra, S.]]
+
[[Category: Misra S]]
-
[[Category: Prag, G.]]
+
[[Category: Prag G]]
-
[[Category: Mono-ubiquitination]]
+
-
[[Category: Post translational modification]]
+
-
[[Category: Trafficking]]
+
-
[[Category: Translation]]
+

Current revision

Mechanism of Ubiquitin Recognition by the CUE Domain of VPS9

PDB ID 1p3q

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools