3mc5
From Proteopedia
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| - | [[Image:3mc5.png|left|200px]] | ||
| - | + | ==Human Aldose Reductase mutant T113V in complex with IDD393 crystallized in spacegroup P1== | |
| - | + | <StructureSection load='3mc5' size='340' side='right'caption='[[3mc5]], [[Resolution|resolution]] 1.14Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3mc5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MC5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.14Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=393:(5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC+ACID'>393</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mc5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mc5 OCA], [https://pdbe.org/3mc5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mc5 RCSB], [https://www.ebi.ac.uk/pdbsum/3mc5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mc5 ProSAT]</span></td></tr> |
| - | [[3mc5]] is a 1 chain structure with sequence from [ | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. | ||
==See Also== | ==See Also== | ||
| - | *[[Aldose | + | *[[Aldose reductase 3D structures|Aldose reductase 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Heine A]] |
| - | [[Category: | + | [[Category: Klebe G]] |
| - | [[Category: | + | [[Category: Koch C]] |
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Current revision
Human Aldose Reductase mutant T113V in complex with IDD393 crystallized in spacegroup P1
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