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1tps

From Proteopedia

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[[Image:1tps.png|left|200px]]
 
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{{STRUCTURE_1tps| PDB=1tps | SCENE= }}
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==ATOMIC STRUCTURE OF THE TRYPSIN-A90720A COMPLEX: A UNIFIED APPROACH TO STRUCTURE AND FUNCTION==
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<StructureSection load='1tps' size='340' side='right'caption='[[1tps]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===ATOMIC STRUCTURE OF THE TRYPSIN-A90720A COMPLEX: A UNIFIED APPROACH TO STRUCTURE AND FUNCTION===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1tps]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Cyanobacteria Cyanobacteria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TPS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TPS FirstGlance]. <br>
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{{ABSTRACT_PUBMED_9383379}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=OSL:(2R)-2-HYDROXY-3-(SULFOOXY)PROPANOIC+ACID'>OSL</scene>, <scene name='pdbligand=YNM:N-METHYL-L-TYROSINE'>YNM</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tps OCA], [https://pdbe.org/1tps PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tps RCSB], [https://www.ebi.ac.uk/pdbsum/1tps PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tps ProSAT]</span></td></tr>
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[[1tps]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Cyanobacteria Cyanobacteria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TPS OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tp/1tps_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tps ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Trypsin|Trypsin]]
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*[[Trypsin 3D structures|Trypsin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:009383379</ref><references group="xtra"/>
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Cyanobacteria]]
[[Category: Cyanobacteria]]
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[[Category: Clardy, J.]]
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[[Category: Large Structures]]
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[[Category: Lee, A Y.]]
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[[Category: Clardy J]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Lee AY]]
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[[Category: Serine protease]]
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Current revision

ATOMIC STRUCTURE OF THE TRYPSIN-A90720A COMPLEX: A UNIFIED APPROACH TO STRUCTURE AND FUNCTION

PDB ID 1tps

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