3tvu

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[[Image:3tvu.png|left|200px]]
 
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{{STRUCTURE_3tvu| PDB=3tvu | SCENE= }}
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==Crystal Structure of the humanized carboxyltransferase domain of yeast Acetyl-coA caroxylase in complex with compound 3==
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<StructureSection load='3tvu' size='340' side='right'caption='[[3tvu]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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===Crystal Structure of the humanized carboxyltransferase domain of yeast Acetyl-coA caroxylase in complex with compound 3===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3tvu]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TVU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TVU FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21953464}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B37:4-({4-[(2-METHYLQUINOLIN-6-YL)METHYL]PIPERIDIN-1-YL}CARBONYL)-2-PHENYLQUINOLINE'>B37</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tvu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tvu OCA], [https://pdbe.org/3tvu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tvu RCSB], [https://www.ebi.ac.uk/pdbsum/3tvu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tvu ProSAT]</span></td></tr>
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[[3tvu]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TVU OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACAC_YEAST ACAC_YEAST] Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole.<ref>PMID:6108218</ref> <ref>PMID:6103540</ref> <ref>PMID:8943372</ref> <ref>PMID:10757783</ref> <ref>PMID:12730220</ref>
==See Also==
==See Also==
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*[[Acetyl-CoA carboxylase|Acetyl-CoA carboxylase]]
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*[[Acetyl-CoA carboxylase 3D structures|Acetyl-CoA carboxylase 3D structures]]
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*[[Biotin carboxylase|Biotin carboxylase]]
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== References ==
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<references/>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:021953464</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Saccharomyces cerevisiae s288c]]
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[[Category: Large Structures]]
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[[Category: Anderson, M D]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Corbett, J W.]]
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[[Category: Anderson MD]]
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[[Category: Dirico, K J.]]
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[[Category: Corbett JW]]
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[[Category: Harwood, J H.]]
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[[Category: Dirico KJ]]
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[[Category: Landro, J A.]]
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[[Category: Harwood JH]]
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[[Category: Marr, E.]]
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[[Category: Landro JA]]
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[[Category: Rajamohan, F.]]
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[[Category: Marr E]]
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[[Category: Reyes, A.]]
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[[Category: Rajamohan F]]
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[[Category: Tu, M.]]
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[[Category: Reyes A]]
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[[Category: Vajdos, F F.]]
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[[Category: Tu M]]
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[[Category: Carboxyltransferase]]
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[[Category: Vajdos FF]]
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[[Category: Ligase]]
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Current revision

Crystal Structure of the humanized carboxyltransferase domain of yeast Acetyl-coA caroxylase in complex with compound 3

PDB ID 3tvu

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