1wwh

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[[Image:1wwh.png|left|200px]]
 
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{{STRUCTURE_1wwh| PDB=1wwh | SCENE= }}
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==Crystal structure of the MPPN domain of mouse Nup35==
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<StructureSection load='1wwh' size='340' side='right'caption='[[1wwh]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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===Crystal structure of the MPPN domain of mouse Nup35===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1wwh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WWH FirstGlance]. <br>
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{{ABSTRACT_PUBMED_16962612}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wwh OCA], [https://pdbe.org/1wwh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wwh RCSB], [https://www.ebi.ac.uk/pdbsum/1wwh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wwh ProSAT], [https://www.topsan.org/Proteins/RSGI/1wwh TOPSAN]</span></td></tr>
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==About this Structure==
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</table>
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[[1wwh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WWH OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/NUP35_MOUSE NUP35_MOUSE] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ww/1wwh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wwh ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Nucleoporin|Nucleoporin]]
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*[[Nucleoporin 3D structures|Nucleoporin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:016962612</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Hamana, H.]]
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[[Category: Hamana H]]
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[[Category: Handa, N.]]
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[[Category: Handa N]]
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[[Category: Kukimoto, M.]]
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[[Category: Kukimoto M]]
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[[Category: Murayama, K.]]
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[[Category: Murayama K]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Shirouzu M]]
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[[Category: Shirouzu, M.]]
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[[Category: Takemoto C]]
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[[Category: Takemoto, C.]]
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[[Category: Terada T]]
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[[Category: Terada, T.]]
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[[Category: Uchikubo T]]
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[[Category: Uchikubo, T.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: Mppn]]
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[[Category: Protein transport]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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Current revision

Crystal structure of the MPPN domain of mouse Nup35

PDB ID 1wwh

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