2a62
From Proteopedia
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| - | [[Image:2a62.png|left|200px]] | ||
| - | + | ==Crystal structure of mouse cadherin-8 EC1-3== | |
| - | + | <StructureSection load='2a62' size='340' side='right'caption='[[2a62]], [[Resolution|resolution]] 4.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2a62]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A62 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.5Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a62 OCA], [https://pdbe.org/2a62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a62 RCSB], [https://www.ebi.ac.uk/pdbsum/2a62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a62 ProSAT]</span></td></tr> |
| - | [[2a62]] is a 1 chain structure with sequence from [ | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CADH8_MOUSE CADH8_MOUSE] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a6/2a62_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a62 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Cadherin|Cadherin]] | + | *[[Cadherin 3D structures|Cadherin 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | < | + | [[Category: Large Structures]] |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Arkus | + | [[Category: Arkus N]] |
| - | [[Category: Bahna | + | [[Category: Bahna F]] |
| - | [[Category: Chen | + | [[Category: Chen CP]] |
| - | [[Category: Ciatto | + | [[Category: Ciatto C]] |
| - | [[Category: Honig | + | [[Category: Honig B]] |
| - | [[Category: Jessell | + | [[Category: Jessell TM]] |
| - | [[Category: Patel | + | [[Category: Patel SD]] |
| - | [[Category: Price | + | [[Category: Price SR]] |
| - | [[Category: Schieren | + | [[Category: Schieren I]] |
| - | [[Category: Shapiro | + | [[Category: Shapiro L]] |
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Current revision
Crystal structure of mouse cadherin-8 EC1-3
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Categories: Large Structures | Mus musculus | Arkus N | Bahna F | Chen CP | Ciatto C | Honig B | Jessell TM | Patel SD | Price SR | Schieren I | Shapiro L
