1t0m
From Proteopedia
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| - | [[Image:1t0m.png|left|200px]] | ||
| - | + | ==Conformational switch in polymorphic H-2K molecules containing an HSV peptide== | |
| - | + | <StructureSection load='1t0m' size='340' side='right'caption='[[1t0m]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1t0m]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_alphaherpesvirus_1_strain_F Human alphaherpesvirus 1 strain F] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T0M FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t0m OCA], [https://pdbe.org/1t0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t0m RCSB], [https://www.ebi.ac.uk/pdbsum/1t0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t0m ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1t0m]] is a 6 chain structure with sequence from [ | + | == Function == |
| + | [https://www.uniprot.org/uniprot/HA1B_MOUSE HA1B_MOUSE] Involved in the presentation of foreign antigens to the immune system. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t0/1t0m_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t0m ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Beta-2 microglobulin|Beta-2 microglobulin]] | + | *[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]] |
| - | *[[ | + | *[[MHC 3D structures|MHC 3D structures]] |
| - | + | *[[MHC I 3D structures|MHC I 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| + | [[Category: Human alphaherpesvirus 1 strain F]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Beddoe | + | [[Category: Beddoe T]] |
| - | [[Category: Borg | + | [[Category: Borg NA]] |
| - | [[Category: Bottomley | + | [[Category: Bottomley SP]] |
| - | [[Category: Carbone | + | [[Category: Carbone FR]] |
| - | [[Category: Dunstone | + | [[Category: Dunstone MA]] |
| - | [[Category: Kjer-Nielsen | + | [[Category: Kjer-Nielsen L]] |
| - | [[Category: McCluskey | + | [[Category: McCluskey J]] |
| - | [[Category: Purcell | + | [[Category: Purcell AW]] |
| - | [[Category: Rossjohn | + | [[Category: Rossjohn J]] |
| - | [[Category: Webb | + | [[Category: Webb AI]] |
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Current revision
Conformational switch in polymorphic H-2K molecules containing an HSV peptide
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