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2kua

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[[Image:2kua.png|left|200px]]
 
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{{STRUCTURE_2kua| PDB=2kua | SCENE= }}
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==Solution structure of a divergent Bcl-2 protein==
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<StructureSection load='2kua' size='340' side='right'caption='[[2kua]]' scene=''>
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===Solution structure of a divergent Bcl-2 protein===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2kua]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KUA FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kua OCA], [https://pdbe.org/2kua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kua RCSB], [https://www.ebi.ac.uk/pdbsum/2kua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kua ProSAT]</span></td></tr>
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[[2kua]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KUA OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/B2L10_MOUSE B2L10_MOUSE] Promotes cell survival. Suppresses apoptosis.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ku/2kua_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kua ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Bcl-2|Bcl-2]]
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*[[B-cell lymphoma proteins 3D structures|B-cell lymphoma proteins 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:020455273</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Day, C L.]]
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[[Category: Day CL]]
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[[Category: Hinds, M G.]]
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[[Category: Hinds MG]]
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[[Category: Rautureau, G J.]]
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[[Category: Rautureau GJ]]
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[[Category: Apoptosis]]
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[[Category: Bcl-2]]
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[[Category: Bh3-only]]
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[[Category: Boo]]
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[[Category: Diva]]
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[[Category: Membrane]]
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[[Category: Mitochondrion]]
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[[Category: Nucleus]]
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[[Category: Transmembrane]]
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Current revision

Solution structure of a divergent Bcl-2 protein

PDB ID 2kua

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