2lf1

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[[Image:2lf1.png|left|200px]]
 
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{{STRUCTURE_2lf1| PDB=2lf1 | SCENE= }}
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==Solution structure of L. casei dihydrofolate reductase complexed with NADPH, 30 structures==
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<StructureSection load='2lf1' size='340' side='right'caption='[[2lf1]]' scene=''>
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===Solution structure of L. casei dihydrofolate reductase complexed with NADPH, 30 structures===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2lf1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lacticaseibacillus_casei Lacticaseibacillus casei]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LF1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LF1 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21410224}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lf1 OCA], [https://pdbe.org/2lf1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lf1 RCSB], [https://www.ebi.ac.uk/pdbsum/2lf1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lf1 ProSAT]</span></td></tr>
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[[2lf1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_casei Lactobacillus casei]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LF1 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DYR_LACCA DYR_LACCA] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
==See Also==
==See Also==
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*[[Dihydrofolate reductase|Dihydrofolate reductase]]
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*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021410224</ref><references group="xtra"/>
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[[Category: Lacticaseibacillus casei]]
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[[Category: Dihydrofolate reductase]]
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[[Category: Large Structures]]
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[[Category: Lactobacillus casei]]
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[[Category: Birdsall B]]
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[[Category: Birdsall, B.]]
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[[Category: Feeney J]]
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[[Category: Feeney, J.]]
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[[Category: Kovalevskaya N]]
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[[Category: Kovalevskaya, N.]]
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[[Category: Polshakov V]]
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[[Category: Polshakov, V.]]
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[[Category: Dhfr]]
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[[Category: Oxidoreductase]]
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[[Category: Positive cooperativity]]
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[[Category: Protein-ligand interaction]]
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Current revision

Solution structure of L. casei dihydrofolate reductase complexed with NADPH, 30 structures

PDB ID 2lf1

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