3qkr

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[[Image:3qkr.png|left|200px]]
 
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{{STRUCTURE_3qkr| PDB=3qkr | SCENE= }}
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==Mre11 Rad50 binding domain bound to Rad50==
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<StructureSection load='3qkr' size='340' side='right'caption='[[3qkr]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
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===Mre11 Rad50 binding domain bound to Rad50===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3qkr]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QKR FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21441914}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qkr OCA], [https://pdbe.org/3qkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qkr RCSB], [https://www.ebi.ac.uk/pdbsum/3qkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qkr ProSAT]</span></td></tr>
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[[3qkr]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QKR OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RAD50_PYRFU RAD50_PYRFU] Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site.[HAMAP-Rule:MF_00449]
==See Also==
==See Also==
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*[[ATPase|ATPase]]
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*[[ATPase 3D structures|ATPase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021441914</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
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[[Category: Arvai, A.]]
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[[Category: Arvai A]]
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[[Category: Moncalian, G.]]
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[[Category: Moncalian G]]
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[[Category: Tainer, J A.]]
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[[Category: Tainer JA]]
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[[Category: Williams, G J.]]
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[[Category: Williams GJ]]
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[[Category: Williams, R S.]]
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[[Category: Williams RS]]
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[[Category: Atp binding]]
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[[Category: Atpase]]
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[[Category: Coiled-coil]]
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[[Category: Dna binding]]
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[[Category: Endonuclease]]
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[[Category: Exonuclease]]
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[[Category: Reca-like fold]]
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[[Category: Replication]]
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Current revision

Mre11 Rad50 binding domain bound to Rad50

PDB ID 3qkr

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