2cy3

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[[Image:2cy3.png|left|200px]]
 
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{{STRUCTURE_2cy3| PDB=2cy3 | SCENE= }}
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==CRYSTAL STRUCTURE OF CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS NORWAY AT 1.7 ANGSTROMS RESOLUTION==
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<StructureSection load='2cy3' size='340' side='right'caption='[[2cy3]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2cy3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfomicrobium_norvegicum Desulfomicrobium norvegicum]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1cy3 1cy3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CY3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CY3 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cy3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cy3 OCA], [https://pdbe.org/2cy3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cy3 RCSB], [https://www.ebi.ac.uk/pdbsum/2cy3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cy3 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CYC31_DESNO CYC31_DESNO] Participates in sulfate respiration coupled with phosphorylation by transferring electrons from the enzyme dehydrogenase to ferredoxin.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cy/2cy3_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cy3 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structure of cytochrome c3 (M(r) 13,000) from Desulfovibrio desulfuricans (118 residues, four heme groups) has been crystallographically refined to 1.7 A resolution using a simulated annealing method, based on the structure-model at 2.5 A resolution, already published. The final R-factor for 10,549 reflections was 0.198 covering the range from 5.5 to 1.7 A resolution. The individual temperature factors were refined for a total of 1059 protein atoms, together with 126 bound solvent molecules. The structure has been analyzed with respect to its detailed conformational properties, secondary structure features, temperature factor behaviour, bound solvent sites and heme geometry and ligation. The characteristic secondary structures of the polypeptide chain of this molecule are one extended alpha-helix, a short beta-strand and 13 reverse turns. The four heme groups are located in different structural environments, all highly exposed to solvent. The particular structural features of the heme environments are compared to the four hemes of the cytochrome c3 from Desulfovibrio vulgaris Miyazaki.
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===CRYSTAL STRUCTURE OF CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS NORWAY AT 1.7 ANGSTROMS RESOLUTION===
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Crystal structure of cytochrome c3 from Desulfovibrio desulfuricans Norway at 1.7 A resolution.,Czjzek M, Payan F, Guerlesquin F, Bruschi M, Haser R J Mol Biol. 1994 Nov 4;243(4):653-67. PMID:7966289<ref>PMID:7966289</ref>
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{{ABSTRACT_PUBMED_7966289}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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==About this Structure==
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<div class="pdbe-citations 2cy3" style="background-color:#fffaf0;"></div>
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[[2cy3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfomicrobium_norvegicum Desulfomicrobium norvegicum]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1cy3 1cy3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CY3 OCA].
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==See Also==
==See Also==
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*[[Cytochrome c|Cytochrome c]]
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*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:007966289</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Desulfomicrobium norvegicum]]
[[Category: Desulfomicrobium norvegicum]]
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[[Category: Czjzek, M.]]
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[[Category: Large Structures]]
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[[Category: Haser, R.]]
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[[Category: Czjzek M]]
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[[Category: Payan, F.]]
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[[Category: Haser R]]
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[[Category: Payan F]]

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CRYSTAL STRUCTURE OF CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS NORWAY AT 1.7 ANGSTROMS RESOLUTION

PDB ID 2cy3

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