1na6

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[[Image:1na6.png|left|200px]]
 
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{{STRUCTURE_1na6| PDB=1na6 | SCENE= }}
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==Crystal structure of restriction endonuclease EcoRII mutant R88A==
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<StructureSection load='1na6' size='340' side='right'caption='[[1na6]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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===Crystal structure of restriction endonuclease EcoRII mutant R88A===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1na6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NA6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NA6 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_14659759}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1na6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1na6 OCA], [https://pdbe.org/1na6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1na6 RCSB], [https://www.ebi.ac.uk/pdbsum/1na6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1na6 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1na6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NA6 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/T2E2_ECOLX T2E2_ECOLX] Recognizes the double-stranded sequence CCWGG and cleaves before C-1.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/na/1na6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1na6 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Endonuclease|Endonuclease]]
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:014659759</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Type II site-specific deoxyribonuclease]]
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[[Category: Large Structures]]
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[[Category: Chen, L.]]
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[[Category: Chen L]]
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[[Category: Kruger, D H.]]
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[[Category: Kruger DH]]
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[[Category: Meehan, E J.]]
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[[Category: Meehan EJ]]
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[[Category: Mucke, M.]]
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[[Category: Mucke M]]
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[[Category: Reuter, M.]]
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[[Category: Reuter M]]
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[[Category: Wang, Y.]]
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[[Category: Wang Y]]
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[[Category: Zhou, X E.]]
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[[Category: Zhou XE]]
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[[Category: Hydrolase]]
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[[Category: Mutation]]
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[[Category: Replication]]
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[[Category: Site-specific restriction]]
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Current revision

Crystal structure of restriction endonuclease EcoRII mutant R88A

PDB ID 1na6

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