1xhx
From Proteopedia
(Difference between revisions)
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:1xhx.png|left|200px]] | ||
| - | + | ==Phi29 DNA Polymerase, orthorhombic crystal form== | |
| - | + | <StructureSection load='1xhx' size='340' side='right'caption='[[1xhx]], [[Resolution|resolution]] 2.35Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1xhx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_virus_phi29 Bacillus virus phi29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XHX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xhx OCA], [https://pdbe.org/1xhx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xhx RCSB], [https://www.ebi.ac.uk/pdbsum/1xhx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xhx ProSAT]</span></td></tr> |
| - | [[1xhx]] is a 4 chain structure with sequence from [ | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DPOL_BPPH2 DPOL_BPPH2] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xh/1xhx_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xhx ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[DNA polymerase|DNA polymerase]] | + | *[[DNA polymerase 3D structures|DNA polymerase 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Bacillus virus phi29]] | |
| - | [[Category: Bacillus | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Berman AJ]] |
| - | [[Category: Berman | + | [[Category: Blanco L]] |
| - | [[Category: Blanco | + | [[Category: Kamtekar S]] |
| - | [[Category: Kamtekar | + | [[Category: Lazaro JM]] |
| - | [[Category: Lazaro | + | [[Category: Salas M]] |
| - | [[Category: Salas | + | [[Category: Steitz TA]] |
| - | [[Category: Steitz | + | [[Category: Wang J]] |
| - | + | [[Category: De Vega M]] | |
| - | [[Category: Wang | + | |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Phi29 DNA Polymerase, orthorhombic crystal form
| |||||||||||
Categories: Bacillus virus phi29 | Large Structures | Berman AJ | Blanco L | Kamtekar S | Lazaro JM | Salas M | Steitz TA | Wang J | De Vega M
