3nh5

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[[Image:3nh5.png|left|200px]]
 
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{{STRUCTURE_3nh5| PDB=3nh5 | SCENE= }}
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==Crystal structure of E177A-mutant murine aminoacylase 3==
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<StructureSection load='3nh5' size='340' side='right'caption='[[3nh5]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
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===Crystal structure of E177A-mutant murine aminoacylase 3===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3nh5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NH5 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_20921362}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.094&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nh5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nh5 OCA], [https://pdbe.org/3nh5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nh5 RCSB], [https://www.ebi.ac.uk/pdbsum/3nh5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nh5 ProSAT]</span></td></tr>
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[[3nh5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NH5 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACY3_MOUSE ACY3_MOUSE] Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids.<ref>PMID:14656720</ref> <ref>PMID:17012540</ref>
==See Also==
==See Also==
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*[[Aspartoacylase|Aspartoacylase]]
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*[[Aminoacylase 3D structures|Aminoacylase 3D structures]]
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*[[Aspartoacylase 3D structures|Aspartoacylase 3D structures]]
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==Reference==
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== References ==
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<ref group="xtra">PMID:020921362</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Abramson, J.]]
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[[Category: Abramson J]]
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[[Category: Abuladze, N.]]
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[[Category: Abuladze N]]
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[[Category: Hsieh, J M.]]
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[[Category: Hsieh JM]]
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[[Category: Kurtz, I.]]
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[[Category: Kurtz I]]
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[[Category: Magilnick, N.]]
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[[Category: Magilnick N]]
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[[Category: Pushkin, A.]]
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[[Category: Pushkin A]]
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[[Category: Sawaya, M R.]]
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[[Category: Sawaya MR]]
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[[Category: Tsirulnikov, K.]]
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[[Category: Tsirulnikov K]]
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[[Category: Hydrolase]]
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[[Category: Mercapturate]]
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Current revision

Crystal structure of E177A-mutant murine aminoacylase 3

PDB ID 3nh5

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