2dfs
From Proteopedia
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- | [[Image:2dfs.png|left|200px]] | ||
- | + | ==3-D structure of Myosin-V inhibited state== | |
- | + | <StructureSection load='2dfs' size='340' side='right'caption='[[2dfs]], [[Resolution|resolution]] 24.00Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2dfs]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DFS FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron crystallography, [[Resolution|Resolution]] 24Å</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dfs OCA], [https://pdbe.org/2dfs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dfs RCSB], [https://www.ebi.ac.uk/pdbsum/2dfs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dfs ProSAT]</span></td></tr> | |
- | == | + | </table> |
- | [[2dfs]] is a 14 chain structure with sequence from [ | + | == Function == |
+ | [https://www.uniprot.org/uniprot/MYO5A_CHICK MYO5A_CHICK] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation (By similarity). | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/2dfs_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dfs ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
- | *[[Calmodulin|Calmodulin]] | + | *[[Calmodulin 3D structures|Calmodulin 3D structures]] |
- | *[[Myosin|Myosin]] | + | *[[Myosin 3D Structures|Myosin 3D Structures]] |
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | + | ||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
- | [[Category: Krementsova | + | [[Category: Krementsova EB]] |
- | [[Category: Liu | + | [[Category: Liu J]] |
- | [[Category: Taylor | + | [[Category: Taylor DW]] |
- | [[Category: Taylor | + | [[Category: Taylor KA]] |
- | [[Category: Trybus | + | [[Category: Trybus KM]] |
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Current revision
3-D structure of Myosin-V inhibited state
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