3bt8

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[[Image:3bt8.png|left|200px]]
 
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{{STRUCTURE_3bt8| PDB=3bt8 | SCENE= }}
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==Crystal Structure of Mutant Cyclophilin (R147A) from Leishmania donovani==
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<StructureSection load='3bt8' size='340' side='right'caption='[[3bt8]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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===Crystal Structure of Mutant Cyclophilin (R147A) from Leishmania donovani===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3bt8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_donovani Leishmania donovani]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BT8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BT8 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_17277440}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bt8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bt8 OCA], [https://pdbe.org/3bt8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bt8 RCSB], [https://www.ebi.ac.uk/pdbsum/3bt8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bt8 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[3bt8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_donovani Leishmania donovani]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BT8 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/Q9U9R3_LEIDO Q9U9R3_LEIDO] PPIases accelerate the folding of proteins.[RuleBase:RU000493] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.[RuleBase:RU004223]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bt/3bt8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bt8 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Cyclophilin|Cyclophilin]]
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*[[Cyclophilin 3D structures|Cyclophilin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:017277440</ref><ref group="xtra">PMID:017552497</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Leishmania donovani]]
[[Category: Leishmania donovani]]
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[[Category: Peptidylprolyl isomerase]]
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[[Category: Banerjee R]]
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[[Category: Banerjee, R.]]
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[[Category: Datta AK]]
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[[Category: Datta, A K.]]
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[[Category: Sen B]]
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[[Category: Sen, B.]]
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[[Category: Venugopal V]]
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[[Category: Venugopal, V.]]
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[[Category: Cis-tran]]
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[[Category: Cyclophilin]]
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[[Category: Donovani]]
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[[Category: Isomerase]]
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[[Category: Kala-azar]]
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[[Category: Leishmania]]
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[[Category: Proline]]
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[[Category: Protozoa]]
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[[Category: Rotamase]]
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Current revision

Crystal Structure of Mutant Cyclophilin (R147A) from Leishmania donovani

PDB ID 3bt8

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