2kpf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:47, 1 May 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2kpf.png|left|200px]]
 
-
{{STRUCTURE_2kpf| PDB=2kpf | SCENE= }}
+
==Spatial structure of the dimeric transmembrane domain of glycophorin A in bicelles soluton==
-
 
+
<StructureSection load='2kpf' size='340' side='right'caption='[[2kpf]]' scene=''>
-
===Spatial structure of the dimeric transmembrane domain of glycophorin A in bicelles soluton===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2kpf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KPF FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_22649687}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kpf OCA], [https://pdbe.org/2kpf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kpf RCSB], [https://www.ebi.ac.uk/pdbsum/2kpf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kpf ProSAT]</span></td></tr>
-
==About this Structure==
+
</table>
-
[[2kpf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KPF OCA].
+
== Function ==
 +
[https://www.uniprot.org/uniprot/GLPA_HUMAN GLPA_HUMAN] Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV).<ref>PMID:8009226</ref> <ref>PMID:10926825</ref> <ref>PMID:12813056</ref> <ref>PMID:14604989</ref> <ref>PMID:15331714</ref> <ref>PMID:19438409</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kp/2kpf_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kpf ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Endonuclease|Endonuclease]]
+
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:022649687</ref><references group="xtra"/>
+
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arseniev, A S.]]
+
[[Category: Large Structures]]
-
[[Category: Bocharov, E V.]]
+
[[Category: Arseniev AS]]
-
[[Category: Efremov, R G.]]
+
[[Category: Bocharov EV]]
-
[[Category: Goncharuk, M V.]]
+
[[Category: Efremov RG]]
-
[[Category: Mineev, K S.]]
+
[[Category: Goncharuk MV]]
-
[[Category: Volynsky, P E.]]
+
[[Category: Mineev KS]]
-
[[Category: Bicelle]]
+
[[Category: Volynsky PE]]
-
[[Category: Blood group antigen]]
+
-
[[Category: Cell membrane]]
+
-
[[Category: Glycophorin some]]
+
-
[[Category: Glycoprotein]]
+
-
[[Category: Host-virus interaction]]
+
-
[[Category: Membrane]]
+
-
[[Category: Membrane protein]]
+
-
[[Category: Micelle]]
+
-
[[Category: Sialic acid]]
+
-
[[Category: Transmembrane]]
+
-
[[Category: Transmembrane dimer]]
+

Current revision

Spatial structure of the dimeric transmembrane domain of glycophorin A in bicelles soluton

PDB ID 2kpf

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2kpf"
Personal tools