2f24

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:11, 17 October 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2f24.png|left|200px]]
 
-
{{STRUCTURE_2f24| PDB=2f24 | SCENE= }}
+
==Crystal Structure of the Human Sialidase Neu2 E111Q Mutant==
-
 
+
<StructureSection load='2f24' size='340' side='right'caption='[[2f24]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
-
===Crystal Structure of the Human Sialidase Neu2 E111Q Mutant===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2f24]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F24 FirstGlance]. <br>
-
 
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76&#8491;</td></tr>
-
==About this Structure==
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-
[[2f24]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F24 OCA].
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f24 OCA], [https://pdbe.org/2f24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f24 RCSB], [https://www.ebi.ac.uk/pdbsum/2f24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f24 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/NEUR2_HUMAN NEUR2_HUMAN] Hydrolyzes sialylated compounds.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f2/2f24_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f24 ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Neuraminidase|Neuraminidase]]
+
*[[Neuraminidase 3D structures|Neuraminidase 3D structures]]
-
[[Category: Exo-alpha-sialidase]]
+
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Chavas, L M.G.]]
+
[[Category: Large Structures]]
-
[[Category: Fusi, P.]]
+
[[Category: Chavas LMG]]
-
[[Category: Kato, R.]]
+
[[Category: Fusi P]]
-
[[Category: Monti, E.]]
+
[[Category: Kato R]]
-
[[Category: Tettamanti, G.]]
+
[[Category: Monti E]]
-
[[Category: Tringali, C.]]
+
[[Category: Tettamanti G]]
-
[[Category: Venerando, B.]]
+
[[Category: Tringali C]]
-
[[Category: Wakatsuki, S.]]
+
[[Category: Venerando B]]
-
[[Category: Drug design]]
+
[[Category: Wakatsuki S]]
-
[[Category: Ganglioside]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Neuraminidase]]
+
-
[[Category: Sialidase]]
+

Current revision

Crystal Structure of the Human Sialidase Neu2 E111Q Mutant

PDB ID 2f24

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2f24"
Personal tools