1qu7

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[[Image:1qu7.png|left|200px]]
 
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{{STRUCTURE_1qu7| PDB=1qu7 | SCENE= }}
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==FOUR HELICAL-BUNDLE STRUCTURE OF THE CYTOPLASMIC DOMAIN OF A SERINE CHEMOTAXIS RECEPTOR==
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<StructureSection load='1qu7' size='340' side='right'caption='[[1qu7]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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===FOUR HELICAL-BUNDLE STRUCTURE OF THE CYTOPLASMIC DOMAIN OF A SERINE CHEMOTAXIS RECEPTOR===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1qu7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QU7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QU7 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10466731}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qu7 OCA], [https://pdbe.org/1qu7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qu7 RCSB], [https://www.ebi.ac.uk/pdbsum/1qu7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qu7 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1qu7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QU7 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/MCP1_ECOLI MCP1_ECOLI] Receptor for the attractant L-serine and related amino acids. Is also responsible for chemotaxis away from a wide range of repellents, including leucine, indole, and weak acids. Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation, the methyl groups are added by the methyltransferase CheR and removed by the methylesterase CheB.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qu/1qu7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qu7 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Chemotaxis protein|Chemotaxis protein]]
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*[[Chemotaxis protein 3D structures|Chemotaxis protein 3D structures]]
*[[Methyl-accepting chemotaxis protein|Methyl-accepting chemotaxis protein]]
*[[Methyl-accepting chemotaxis protein|Methyl-accepting chemotaxis protein]]
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*[[Molecular Playground/cytoplasmic domain of a serine chemotaxis receptor|Molecular Playground/cytoplasmic domain of a serine chemotaxis receptor]]
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__TOC__
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:010466731</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Kim, K K.]]
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[[Category: Large Structures]]
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[[Category: Kim, S H.]]
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[[Category: Kim KK]]
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[[Category: Yokota, H.]]
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[[Category: Kim S-H]]
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[[Category: Chemotaxis]]
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[[Category: Yokota H]]
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[[Category: Four helical-bundle]]
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[[Category: Serine]]
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[[Category: Signaling protein]]
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Current revision

FOUR HELICAL-BUNDLE STRUCTURE OF THE CYTOPLASMIC DOMAIN OF A SERINE CHEMOTAXIS RECEPTOR

PDB ID 1qu7

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