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2czw

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[[Image:2czw.png|left|200px]]
 
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{{STRUCTURE_2czw| PDB=2czw | SCENE= }}
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==Crystal structure analysis of protein component Ph1496p of P.horikoshii ribonuclease P==
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<StructureSection load='2czw' size='340' side='right'caption='[[2czw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===Crystal structure analysis of protein component Ph1496p of P.horikoshii ribonuclease P===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2czw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CZW FirstGlance]. <br>
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{{ABSTRACT_PUBMED_16574071}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2czw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2czw OCA], [https://pdbe.org/2czw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2czw RCSB], [https://www.ebi.ac.uk/pdbsum/2czw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2czw ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[2czw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZW OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/RL7A_PYRHO RL7A_PYRHO] Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, box H/ACA, box C/D and box C'/D' sRNAs (By similarity). When added to reconstituted ribonuclease P (RNase P) it increases the optimum temperature to that of the partially purified enzyme and causes a 5-fold increase in apparent Vmax. Binds the RNase P catalytic RNA.<ref>PMID:16829535</ref> <ref>PMID:16574071</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/2czw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2czw ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Ribosomal protein L7|Ribosomal protein L7]]
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*[[Ribosomal protein L7/L12|Ribosomal protein L7/L12]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:016574071</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
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[[Category: Fukuhara, H.]]
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[[Category: Fukuhara H]]
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[[Category: Honda, T.]]
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[[Category: Honda T]]
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[[Category: Kakuta, Y.]]
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[[Category: Kakuta Y]]
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[[Category: Kifusa, M.]]
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[[Category: Kifusa M]]
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[[Category: Kimura, M.]]
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[[Category: Kimura M]]
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[[Category: Numata, T.]]
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[[Category: Numata T]]
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[[Category: Terada, A.]]
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[[Category: Terada A]]
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[[Category: Watanabe, M.]]
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[[Category: Watanabe M]]
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[[Category: Hydrolase]]
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[[Category: Ribonuclease p]]
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[[Category: Ribonucleoprotein]]
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[[Category: Ribosome]]
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Current revision

Crystal structure analysis of protein component Ph1496p of P.horikoshii ribonuclease P

PDB ID 2czw

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