3id0

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[[Image:3id0.png|left|200px]]
 
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{{STRUCTURE_3id0| PDB=3id0 | SCENE= }}
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==Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with 3-Fluoro-1-(2-hydroxy-2,2-bisphosphono-ethyl)pyridinium==
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<StructureSection load='3id0' size='340' side='right'caption='[[3id0]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
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===Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with 3-Fluoro-1-(2-hydroxy-2,2-bisphosphono-ethyl)pyridinium===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3id0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ID0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ID0 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_19876942}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.81&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI9:3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM'>NI9</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3id0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3id0 OCA], [https://pdbe.org/3id0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3id0 RCSB], [https://www.ebi.ac.uk/pdbsum/3id0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3id0 ProSAT]</span></td></tr>
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[[3id0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ID0 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8WS25_TRYCR Q8WS25_TRYCR]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/id/3id0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3id0 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Farnesyl diphosphate synthase|Farnesyl diphosphate synthase]]
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*[[Farnesyl diphosphate synthase 3D structures|Farnesyl diphosphate synthase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:019876942</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Geranyltranstransferase]]
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[[Category: Trypanosoma cruzi]]
[[Category: Trypanosoma cruzi]]
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[[Category: Amzel, L M.]]
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[[Category: Amzel LM]]
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[[Category: Gabelli, S B.]]
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[[Category: Gabelli SB]]
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[[Category: Huang, C H.]]
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[[Category: Huang CH]]
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[[Category: Oldfield, E.]]
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[[Category: Oldfield E]]
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[[Category: Bisphosphonate]]
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[[Category: Chagas disease]]
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[[Category: Farnesyl diphosphate synthase]]
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[[Category: Fpp]]
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[[Category: Isoprene biosynthesis]]
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[[Category: Minodronate]]
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[[Category: Risedronate]]
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[[Category: Transferase]]
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[[Category: Zoledronate]]
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Current revision

Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with 3-Fluoro-1-(2-hydroxy-2,2-bisphosphono-ethyl)pyridinium

PDB ID 3id0

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