2g3h

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[[Image:2g3h.png|left|200px]]
 
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{{STRUCTURE_2g3h| PDB=2g3h | SCENE= }}
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==Cyanide Binding and Heme Cavity Conformational Transitions in Drosophila melanogaster Hexa-coordinate Hemoglobin==
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<StructureSection load='2g3h' size='340' side='right'caption='[[2g3h]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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===Cyanide Binding and Heme Cavity Conformational Transitions in Drosophila melanogaster Hexa-coordinate Hemoglobin===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2g3h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G3H FirstGlance]. <br>
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{{ABSTRACT_PUBMED_16906763}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g3h OCA], [https://pdbe.org/2g3h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g3h RCSB], [https://www.ebi.ac.uk/pdbsum/2g3h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g3h ProSAT]</span></td></tr>
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[[2g3h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3H OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9VF15_DROME Q9VF15_DROME]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g3/2g3h_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g3h ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Hemoglobin|Hemoglobin]]
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*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:016906763</ref><references group="xtra"/>
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[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Ascenzi, P.]]
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[[Category: Large Structures]]
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[[Category: Bocedi, A.]]
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[[Category: Ascenzi P]]
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[[Category: Bolognesi, M.]]
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[[Category: Bocedi A]]
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[[Category: Burmester, T.]]
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[[Category: Bolognesi M]]
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[[Category: Dewilde, S.]]
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[[Category: Burmester T]]
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[[Category: Hankeln, T.]]
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[[Category: Dewilde S]]
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[[Category: Moens, L.]]
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[[Category: Hankeln T]]
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[[Category: Sanctis, D de.]]
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[[Category: Moens L]]
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[[Category: Cyanide binding to hemoglobin]]
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[[Category: De Sanctis D]]
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[[Category: Drosophila melanogaster hemoglobin structure]]
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[[Category: Fruit fly hemoglobin]]
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[[Category: Heme distal site structure]]
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[[Category: Hexa-coordinate hemoglobin]]
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[[Category: Transport protein]]
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Current revision

Cyanide Binding and Heme Cavity Conformational Transitions in Drosophila melanogaster Hexa-coordinate Hemoglobin

PDB ID 2g3h

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