1pn7
From Proteopedia
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| - | [[Image:1pn7.png|left|200px]] | ||
| - | + | ==Coordinates of S12, L11 proteins and P-tRNA, from the 70S X-ray structure aligned to the 70S Cryo-EM map of E.coli ribosome== | |
| - | + | <SX load='1pn7' size='340' side='right' viewer='molstar' caption='[[1pn7]], [[Resolution|resolution]] 10.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1pn7]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] and [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PN7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PN7 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 10.8Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pn7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pn7 OCA], [https://pdbe.org/1pn7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pn7 RCSB], [https://www.ebi.ac.uk/pdbsum/1pn7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pn7 ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1pn7]] is a 3 chain structure with sequence from [ | + | == Function == |
| + | [https://www.uniprot.org/uniprot/RS12_THET8 RS12_THET8] With S4 and S5 plays an important role in translational accuracy (By similarity).[HAMAP-Rule:MF_00403_B] Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.[HAMAP-Rule:MF_00403_B] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pn/1pn7_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pn7 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Ribosomal protein L11|Ribosomal protein L11]] | + | *[[Ribosomal protein L11 3D structures|Ribosomal protein L11 3D structures]] |
*[[Ribosomal protein S12|Ribosomal protein S12]] | *[[Ribosomal protein S12|Ribosomal protein S12]] | ||
| - | + | *[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]] | |
| - | + | __TOC__ | |
| - | < | + | </SX> |
| + | [[Category: Large Structures]] | ||
[[Category: Thermotoga maritima]] | [[Category: Thermotoga maritima]] | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
| - | [[Category: Ehrenberg | + | [[Category: Ehrenberg M]] |
| - | [[Category: Frank | + | [[Category: Frank J]] |
| - | [[Category: Rawat | + | [[Category: Rawat U]] |
| - | [[Category: Sengupta | + | [[Category: Sengupta J]] |
| - | [[Category: Valle | + | [[Category: Valle M]] |
| - | [[Category: Zavialov | + | [[Category: Zavialov A]] |
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Current revision
Coordinates of S12, L11 proteins and P-tRNA, from the 70S X-ray structure aligned to the 70S Cryo-EM map of E.coli ribosome
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