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1eke

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[[Image:1eke.png|left|200px]]
 
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{{STRUCTURE_1eke| PDB=1eke | SCENE= }}
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==CRYSTAL STRUCTURE OF CLASS II RIBONUCLEASE H (RNASE HII) WITH MES LIGAND==
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<StructureSection load='1eke' size='340' side='right'caption='[[1eke]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF CLASS II RIBONUCLEASE H (RNASE HII) WITH MES LIGAND===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1eke]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EKE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EKE FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10997908}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eke OCA], [https://pdbe.org/1eke PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eke RCSB], [https://www.ebi.ac.uk/pdbsum/1eke PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eke ProSAT], [https://www.topsan.org/Proteins/BSGC/1eke TOPSAN]</span></td></tr>
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[[1eke]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EKE OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RNH2_METJA RNH2_METJA] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.[HAMAP-Rule:MF_00052_A]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ek/1eke_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eke ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Ribonuclease|Ribonuclease]]
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:010997908</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
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[[Category: Ribonuclease H]]
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[[Category: Hung LW]]
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[[Category: BSGC, Berkeley Structural Genomics Center.]]
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[[Category: Kim R]]
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[[Category: Hung, L W.]]
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[[Category: Kim SH]]
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[[Category: Kim, R.]]
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[[Category: Lai LH]]
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[[Category: Kim, S H.]]
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[[Category: Yokota H]]
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[[Category: Lai, L H.]]
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[[Category: Yokota, H.]]
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[[Category: Berkeley structural genomics center]]
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[[Category: Bsgc structure funded by nih]]
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[[Category: Endonuclease]]
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[[Category: Hydrolase]]
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[[Category: Nuclease]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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Current revision

CRYSTAL STRUCTURE OF CLASS II RIBONUCLEASE H (RNASE HII) WITH MES LIGAND

PDB ID 1eke

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