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4df8

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[[Image:4df8.png|left|200px]]
 
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{{STRUCTURE_4df8| PDB=4df8 | SCENE= }}
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==Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with aminopentinyl-7-deaza-2-dATP==
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<StructureSection load='4df8' size='340' side='right'caption='[[4df8]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with aminopentinyl-7-deaza-2-dATP===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4df8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DF8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DF8 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22475415}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0L4:5-(5-AMINOPENT-1-YN-1-YL)-7-{2-DEOXY-5-O-[(S)-HYDROXY{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE'>0L4</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DOC:2,3-DIDEOXYCYTIDINE-5-MONOPHOSPHATE'>DOC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4df8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4df8 OCA], [https://pdbe.org/4df8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4df8 RCSB], [https://www.ebi.ac.uk/pdbsum/4df8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4df8 ProSAT]</span></td></tr>
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[[4df8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DF8 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPO1_THEAQ DPO1_THEAQ]
==See Also==
==See Also==
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*[[DNA polymerase|DNA polymerase]]
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:022475415</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Thermus aquaticus]]
[[Category: Thermus aquaticus]]
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[[Category: Baccaro, A.]]
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[[Category: Baccaro A]]
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[[Category: Bergen, K.]]
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[[Category: Bergen K]]
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[[Category: Diederichs, K.]]
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[[Category: Diederichs K]]
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[[Category: Marx, A.]]
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[[Category: Marx A]]
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[[Category: Steck, A.]]
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[[Category: Steck A]]
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[[Category: Struett, S.]]
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[[Category: Struett S]]
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[[Category: Welte, W.]]
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[[Category: Welte W]]
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[[Category: Dna polymerase]]
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[[Category: Transferase-dna complex]]
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Current revision

Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with aminopentinyl-7-deaza-2-dATP

PDB ID 4df8

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