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3gli

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[[Image:3gli.png|left|200px]]
 
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{{STRUCTURE_3gli| PDB=3gli | SCENE= }}
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==Crystal Structure of the E. coli clamp loader bound to Primer-Template DNA and Psi Peptide==
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<StructureSection load='3gli' size='340' side='right'caption='[[3gli]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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===Crystal Structure of the E. coli clamp loader bound to Primer-Template DNA and Psi Peptide===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3gli]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GLI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GLI FirstGlance]. <br>
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{{ABSTRACT_PUBMED_019450514}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gli OCA], [https://pdbe.org/3gli PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gli RCSB], [https://www.ebi.ac.uk/pdbsum/3gli PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gli ProSAT]</span></td></tr>
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[[3gli]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GLI OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HOLB_ECOLI HOLB_ECOLI] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gl/3gli_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gli ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[DNA polymerase|DNA polymerase]]
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:019450514</ref><references group="xtra"/>
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[[Category: Escherichia coli K-12]]
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Large Structures]]
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[[Category: Escherichia coli]]
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[[Category: Cantor AJ]]
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[[Category: Cantor, A J.]]
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[[Category: Kuriyan J]]
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[[Category: Kuriyan, J.]]
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[[Category: Simonetta KR]]
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[[Category: Simonetta, K R.]]
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[[Category: Aaa+ atpase]]
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[[Category: Atp-binding]]
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[[Category: Clamp loader]]
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[[Category: Dna replication]]
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[[Category: Dna-directed dna polymerase]]
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[[Category: Gamma complex]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Psi]]
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[[Category: Replication]]
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[[Category: Transferase]]
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[[Category: Transferase-dna complex]]
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Current revision

Crystal Structure of the E. coli clamp loader bound to Primer-Template DNA and Psi Peptide

PDB ID 3gli

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