3d6c

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[[Image:3d6c.png|left|200px]]
 
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{{STRUCTURE_3d6c| PDB=3d6c | SCENE= }}
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==Crystal structure of Staphylococcal nuclease variant PHS L38E at cryogenic temperature==
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<StructureSection load='3d6c' size='340' side='right'caption='[[3d6c]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===Crystal structure of Staphylococcal nuclease variant PHS L38E at cryogenic temperature===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3d6c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D6C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D6C FirstGlance]. <br>
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{{ABSTRACT_PUBMED_19324049}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d6c OCA], [https://pdbe.org/3d6c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d6c RCSB], [https://www.ebi.ac.uk/pdbsum/3d6c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d6c ProSAT]</span></td></tr>
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[[3d6c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D6C OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d6/3d6c_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d6c ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Staphylococcal nuclease|Staphylococcal nuclease]]
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*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:019324049</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Micrococcal nuclease]]
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[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: E B., Garcia-Moreno.]]
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[[Category: Garcia-Moreno EB]]
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[[Category: Harms, M J.]]
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[[Category: Harms MJ]]
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[[Category: Schlessman, J L.]]
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[[Category: Schlessman JL]]
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[[Category: Sue, G R.]]
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[[Category: Sue GR]]
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[[Category: Endonuclease]]
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[[Category: Hydrolase]]
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[[Category: Hyperstable variant]]
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[[Category: Metal-binding]]
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[[Category: Secreted]]
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[[Category: Staphylococcal nuclease]]
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[[Category: Zymogen]]
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Current revision

Crystal structure of Staphylococcal nuclease variant PHS L38E at cryogenic temperature

PDB ID 3d6c

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