1o4s

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[[Image:1o4s.gif|left|200px]]<br /><applet load="1o4s" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1o4s, resolution 1.90&Aring;" />
 
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'''Crystal structure of Aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 A resolution'''<br />
 
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==About this Structure==
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==Crystal structure of Aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 A resolution==
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1O4S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=PLP:'>PLP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Aspartate_transaminase Aspartate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.1 2.6.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O4S OCA].
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<StructureSection load='1o4s' size='340' side='right'caption='[[1o4s]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1o4s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O4S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O4S FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o4s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o4s OCA], [https://pdbe.org/1o4s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o4s RCSB], [https://www.ebi.ac.uk/pdbsum/1o4s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o4s ProSAT], [https://www.topsan.org/Proteins/JCSG/1o4s TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AAT_THEMA AAT_THEMA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o4/1o4s_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1o4s ConSurf].
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<div style="clear:both"></div>
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==Reference==
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==See Also==
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Crystal structure of an aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 A resolution., Schwarzenbacher R, Jaroszewski L, von Delft F, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Cambell J, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Eshagi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Hampton E, Karlak C, Klock HE, Koesema E, Kovarik JS, Kreusch A, Kuhn P, Lesley SA, Levin I, McMullan D, McPhillips TM, Miller MD, Morse A, Moy K, Ouyang J, Page R, Quijano K, Robb A, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, Wang X, West B, Wolf G, Xu Q, Hodgson KO, Wooley J, Wilson IA, Proteins. 2004 May 15;55(3):759-63. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15103638 15103638]
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*[[Aspartate aminotransferase 3D structures|Aspartate aminotransferase 3D structures]]
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[[Category: Aspartate transaminase]]
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__TOC__
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[[Category: Single protein]]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: JCSG, Joint Center for Structural Genomics.]]
 
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[[Category: PLP]]
 
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[[Category: SO4]]
 
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[[Category: aspartate aminotransferase]]
 
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[[Category: jcsg]]
 
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[[Category: joint center for structural genomics]]
 
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[[Category: protein structure initiative]]
 
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[[Category: psi]]
 
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[[Category: structural genomics]]
 
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[[Category: tm1255]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:13:27 2008''
 

Current revision

Crystal structure of Aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 A resolution

PDB ID 1o4s

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