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3rif

From Proteopedia

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[[Image:3rif.png|left|200px]]
 
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{{STRUCTURE_3rif| PDB=3rif | SCENE= }}
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==C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and glutamate.==
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<StructureSection load='3rif' size='340' side='right'caption='[[3rif]], [[Resolution|resolution]] 3.34&Aring;' scene=''>
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===C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and glutamate.===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3rif]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. The November 2015 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Glutamate-gated Chloride Receptors'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2015_11 10.2210/rcsb_pdb/mom_2015_11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RIF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RIF FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21572436}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.345&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=IVM:(2AE,4E,5S,6S,6R,7S,8E,11R,13R,15S,17AR,20R,20AR,20BS)-6-[(2S)-BUTAN-2-YL]-20,20B-DIHYDROXY-5,6,8,19-TETRAMETHYL-17-OXO-3,4,5,6,6,10,11,14,15,17,17A,20,20A,20B-TETRADECAHYDRO-2H,7H-SPIRO[11,15-METHANOFURO[4,3,2-PQ][2,6]BENZODIOXACYCLOOCTADECINE-13,2-PYRAN]-7-YL+2,6-DIDEOXY-4-O-(2,6-DIDEOXY-3-O-METHYL-ALPHA-L-ARABINO-HEXOPYRANOSYL)-3-O-METHYL-ALPHA-L-ARABINO-HEXOPYRANOSIDE'>IVM</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OCT:N-OCTANE'>OCT</scene>, <scene name='pdbligand=UND:UNDECANE'>UND</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rif OCA], [https://pdbe.org/3rif PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rif RCSB], [https://www.ebi.ac.uk/pdbsum/3rif PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rif ProSAT]</span></td></tr>
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[[3rif]] is a 15 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RIF OCA].
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</table>
==See Also==
==See Also==
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*[[Monoclonal Antibody|Monoclonal Antibody]]
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*[[Ion channels 3D structures|Ion channels 3D structures]]
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:021572436</ref><references group="xtra"/>
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</StructureSection>
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
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[[Category: Glutamate-gated Chloride Receptors]]
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Gouaux, E.]]
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[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Hibbs, R E.]]
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[[Category: Gouaux E]]
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[[Category: Cys-loop receptor]]
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[[Category: Hibbs RE]]
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[[Category: Glycosylation]]
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[[Category: Ivermectin]]
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[[Category: Ligand-gated ion channel]]
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[[Category: Membrane protein]]
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[[Category: Neurotransmitter receptor]]
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[[Category: Picrotoxin]]
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[[Category: Transport protein]]
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[[Category: Transport protein-immune system complex]]
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Current revision

C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and glutamate.

PDB ID 3rif

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