This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3ccv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:34, 21 February 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3ccv.png|left|200px]]
 
-
{{STRUCTURE_3ccv| PDB=3ccv | SCENE= }}
+
==Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2616A==
-
 
+
<StructureSection load='3ccv' size='340' side='right'caption='[[3ccv]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-
===Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2616A===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[3ccv]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CCV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CCV FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_18455733}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1MA:6-HYDRO-1-METHYLADENOSINE-5-MONOPHOSPHATE'>1MA</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=SR:STRONTIUM+ION'>SR</scene>, <scene name='pdbligand=UR3:3-METHYLURIDINE-5-MONOPHOSHATE'>UR3</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ccv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ccv OCA], [https://pdbe.org/3ccv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ccv RCSB], [https://www.ebi.ac.uk/pdbsum/3ccv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ccv ProSAT]</span></td></tr>
-
[[3ccv]] is a 30 chain structure with sequence from [http://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CCV OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/RL5_HALMA RL5_HALMA] This is 1 of 5 proteins that mediates the attachment of the 5S rRNA onto the large ribosomal subunit, stabilizing the orientation of adjacent RNA domains. Forms part of the central protuberance. Modeling places the A and P site tRNAs in close proximity to this protein; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. In the 70S ribosome it is thought to contact protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.[HAMAP-Rule:MF_01333_A]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cc/3ccv_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ccv ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Ribosomal protein L10|Ribosomal protein L10]]
+
*[[Ribosome 3D structures|Ribosome 3D structures]]
-
*[[Ribosomal protein L11|Ribosomal protein L11]]
+
__TOC__
-
*[[Ribosomal protein L13|Ribosomal protein L13]]
+
</StructureSection>
-
*[[Ribosomal protein L14|Ribosomal protein L14]]
+
-
*[[Ribosomal protein L19|Ribosomal protein L19]]
+
-
*[[Ribosomal protein L2|Ribosomal protein L2]]
+
-
*[[Ribosomal protein L21|Ribosomal protein L21]]
+
-
*[[Ribosomal protein L3|Ribosomal protein L3]]
+
-
*[[Ribosomal protein L34|Ribosomal protein L34]]
+
-
*[[Ribosomal protein L4|Ribosomal protein L4]]
+
-
*[[Ribosomal protein L5|Ribosomal protein L5]]
+
-
*[[Ribosomal protein L6|Ribosomal protein L6]]
+
-
*[[Ribosomal protein L7|Ribosomal protein L7]]
+
-
*[[Ribosome|Ribosome]]
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:018455733</ref><references group="xtra"/>
+
[[Category: Haloarcula marismortui]]
[[Category: Haloarcula marismortui]]
-
[[Category: Blaha, G.]]
+
[[Category: Large Structures]]
-
[[Category: Gurel, G.]]
+
[[Category: Blaha G]]
-
[[Category: 23s rrna]]
+
[[Category: Gurel G]]
-
[[Category: G2616a mutation]]
+
-
[[Category: Large ribosomal subunit]]
+
-
[[Category: Ribosome]]
+

Current revision

Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2616A

PDB ID 3ccv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3ccv"
Personal tools