3l21

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[[Image:3l21.png|left|200px]]
 
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{{STRUCTURE_3l21| PDB=3l21 | SCENE= }}
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==The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (DAPA, RV2753C) from Mycobacterium Tuberculosis - DHDPS-A204R==
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<StructureSection load='3l21' size='340' side='right'caption='[[3l21]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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===The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (DAPA, RV2753C) from Mycobacterium Tuberculosis - DHDPS-A204R===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3l21]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L21 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KPI:(2S)-2-AMINO-6-[(1-HYDROXY-1-OXO-PROPAN-2-YLIDENE)AMINO]HEXANOIC+ACID'>KPI</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[3l21]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L21 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l21 OCA], [https://pdbe.org/3l21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l21 RCSB], [https://www.ebi.ac.uk/pdbsum/3l21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l21 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DAPA_MYCTU DAPA_MYCTU] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA) (Probable).<ref>PMID:18062777</ref>
==See Also==
==See Also==
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*[[Dihydrodipicolinate Synthase|Dihydrodipicolinate Synthase]]
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*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
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[[Category: Dihydrodipicolinate synthase]]
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== References ==
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[[Category: Mycobacterium tuberculosis]]
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<references/>
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[[Category: Devenish, S R.]]
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__TOC__
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[[Category: Evans, G L.]]
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</StructureSection>
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[[Category: Gerrard, J A.]]
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[[Category: Large Structures]]
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[[Category: Jamerson, G B.]]
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[[Category: Schuldt, L.]]
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[[Category: Weiss, M S.]]
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[[Category: Amino-acid biosynthesis]]
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[[Category: Dapa]]
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[[Category: Dhdp]]
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[[Category: Diaminopimelate biosynthesis]]
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[[Category: Dihydrodipicolinate synthase]]
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[[Category: Dimer]]
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[[Category: Lyase]]
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[[Category: Lysine biosynthesis]]
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[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Rv2753c]]
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[[Category: Devenish SR]]
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[[Category: Schiff base]]
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[[Category: Evans GL]]
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[[Category: Transferase]]
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[[Category: Gerrard JA]]
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[[Category: Jamerson GB]]
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[[Category: Schuldt L]]
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[[Category: Weiss MS]]

Current revision

The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (DAPA, RV2753C) from Mycobacterium Tuberculosis - DHDPS-A204R

PDB ID 3l21

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