1o0j
From Proteopedia
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{{Theoretical_model}} | {{Theoretical_model}} | ||
| - | [[ | + | ==HUMAN T-CELL LEUKEMIA VIRUS TYPE I PROTEASE (HTLV-I) WITH BOUND CAPSID/NUCLEOCAPSID (CA/NC) SUBSTRATE== |
| + | <StructureSection load='1o0j' size='340' side='right'caption='[[1o0j]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O0J FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o0j FirstGlance], [https://www.ebi.ac.uk/pdbsum/1o0j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o0j ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Sequence alignment of human T-lymphotropic virus type I (HTLV-I) protease and other retroviral proteases reveals that the leukemia virus proteases contain residues at the C-terminus that are absent in the other proteases. We have prepared a mutant of HTLV-I protease that does not contain the 10 C-terminal residues and demonstrated that the catalytic efficiency of cleavage of a peptide substrate is unaffected. | ||
| - | + | The 10 C-terminal residues of HTLV-I protease are not necessary for enzymatic activity.,Herger BE, Mariani VL, Dennison K, Shuker SB Biochem Biophys Res Commun. 2004 Aug 6;320(4):1306-8. PMID:15303275<ref>PMID:15303275</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 1o0j" style="background-color:#fffaf0;"></div> | |
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Theoretical Model]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Dennison, K]] | [[Category: Dennison, K]] | ||
[[Category: Herger, B E]] | [[Category: Herger, B E]] | ||
[[Category: Shuker, S B]] | [[Category: Shuker, S B]] | ||
Current revision
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HUMAN T-CELL LEUKEMIA VIRUS TYPE I PROTEASE (HTLV-I) WITH BOUND CAPSID/NUCLEOCAPSID (CA/NC) SUBSTRATE
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