We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

1ofx

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:01, 14 February 2024) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1ofx.jpg|left|200px]]<br /><applet load="1ofx" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="1ofx, resolution 2.000&Aring;" />
 
-
'''CRYSTAL STRUCTURE OF AN OKAZAKI FRAGMENT AT 2 ANGSTROMS RESOLUTION'''<br />
 
-
==Overview==
+
==CRYSTAL STRUCTURE OF AN OKAZAKI FRAGMENT AT 2 ANGSTROMS RESOLUTION==
-
In DNA replication, Okazaki fragments are formed as double-stranded intermediates during synthesis of the lagging strand. They are composed of the growing DNA strand primed by RNA and the template strand. The DNA oligonucleotide d(GGGTATACGC) and the chimeric RNA-DNA oligonucleotide r(GCG)d(TATACCC) were combined to form a synthetic Okazaki fragment and its three-dimensional structure was determined by x-ray crystallography. The fragment adopts an overall A-type conformation with 11 residues per turn. Although the base-pair geometry, particularly in the central TATA part, is distorted, there is no evidence for a transition from the A- to the B-type conformation at the junction between RNA.DNA hybrid and DNA duplex. The RNA trimer may, therefore, lock the complete fragment in an A-type conformation.
+
<StructureSection load='1ofx' size='340' side='right'caption='[[1ofx]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==About this Structure==
+
<table><tr><td colspan='2'>[[1ofx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OFX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OFX FirstGlance]. <br>
-
1OFX is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=SPM:'>SPM</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OFX OCA].
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
-
==Reference==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ofx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ofx OCA], [https://pdbe.org/1ofx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ofx RCSB], [https://www.ebi.ac.uk/pdbsum/1ofx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ofx ProSAT]</span></td></tr>
-
Crystal structure of an Okazaki fragment at 2-A resolution., Egli M, Usman N, Zhang SG, Rich A, Proc Natl Acad Sci U S A. 1992 Jan 15;89(2):534-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=1370582 1370582]
+
</table>
-
[[Category: Protein complex]]
+
__TOC__
-
[[Category: Egli, M.]]
+
</StructureSection>
-
[[Category: Rich, A.]]
+
[[Category: Large Structures]]
-
[[Category: Usman, N.]]
+
[[Category: Egli M]]
-
[[Category: Zhang, S.]]
+
[[Category: Rich A]]
-
[[Category: SPM]]
+
[[Category: Usman N]]
-
[[Category: a-dna/rna]]
+
[[Category: Zhang S]]
-
[[Category: double helix]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:17:22 2008''
+

Current revision

CRYSTAL STRUCTURE OF AN OKAZAKI FRAGMENT AT 2 ANGSTROMS RESOLUTION

PDB ID 1ofx

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ofx"
Personal tools